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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7527da4950d7e3650aab288853318f5fb1f51f1c2226a823c2b17c1cc5c9f22e' 
  AND token = 'fQFEoLO/7iTpx0adb+9Yy9LiNVwukdq9ZaktYxCjpog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}