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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afce0e65b220b421d29ac657c81a6a39ed6955ce1d64061de644403e93d64a42' 
  AND token = '83s/GXVEKG9Me935ZVb5MyeCis7D3r486x7xILbaNFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}