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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0045157c290ed33a4105ec9875efb38a4f167e0f9fbf72777f4291ac133924d0' 
  AND token = 'QsTv7vagcU0s9yzBt3WoEA2KRy2+jqD1Fdp56p80HXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}