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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5355df4258c63ba471b395dc94fcb2c3244630ed25523d88a9a20a201ba5ae4c' 
  AND token = 'CPZ2R/1geCtc4/Rum2JgLqzVhCTgck5ZKB8kgy1pE5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}