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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65be0db71538ccd7daf994b3749189854285253a41321d4ae90de7b6a35069d5' 
  AND token = 'r5aNOA1kvPq0SgnNY+mr26RHRjMNivD1OIOvcdCQgUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}