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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c635d4ed994d513ec0b92eea9ce3d53061f0d6ddce166b4736a1b6e05801141' 
  AND token = 'JeOtx8cZnVCIQnT/fJglB1/4jTsfaWm6ee6Gjj+I5Jw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}