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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8732540ef52536a7895619a691daaea4fdf114781b4d75d18c0ff27dc2ea7b28' 
  AND token = 'tuWysVIWB7CRsTmnwrJmDlv0t0YS/U/XrPD0LOhCeeM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}