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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3087d194db09c5196e7acbe3e0d8161f57987617740fca122bb81dac930e3305' 
  AND token = 'uw7hU/rZTZU/4GtaTFlMKUV+rEMM5nAT6cweVPqlB4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}