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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57f68be4ad0359ef0782fd73bf39252d6fcf35f663828f48818ee7c9d2276da2' 
  AND token = '57k1fVp/nXORO+jCLMRjN2vUtOsxIMdiiURTxZaUYOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}