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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fa1d05511252789bbe0835eedf5ac788d02e4cf130fcf45a6da73dd2eb5ee3a' 
  AND token = 'LDm8u5p6Y/NS5UOOl6PoXoDd1W3WX4nNTNxW/H3qMs8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}