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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a2cef39f34a722795150f75e3e10213fd2e91318a8c13549c8e446569cb2292' 
  AND token = '4sCr2EN+c/+9n6806gIwBplEB/d9fMdgreoX5RhO8NU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}