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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '790ae7c8fa8788b1737f336dc14afd12abdad6a45efd0f2a8ac374b4d3a13333' 
  AND token = '6tfWhlHDHYCEi2zhBWVC1pZYrXqKWag5phhfR1Ckb64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}