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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df8eb2c2c7d47607c4a5b705e08e82a066d1c4dcc03b3a7615052293c0975842' 
  AND token = 'IJgoT9YFx0EnNldV8Hm+rCesXjcoLJERKNXMUCGXIOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}