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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88e11f27f4032bfeac11abc2835f3a92e6c6775a84dee939644531918b7d0a7e' 
  AND token = 'rgCDsuHRMItUev1Q6LEGMrO15hwMzQtg0qCh9jEqQMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}