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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a48e40513695c308855fa7b8d7e97bc160535f645f2bd2283b40638d8c4e0ce' 
  AND token = 'z0ladlqj2DaZerQn6lLiAp0s2YxaeaJZw00wTTMdHBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}