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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b181e71f0a8064d5abbf1c71aac9c336d3b81a9c26b2e63a7a5f403f33cddc0' 
  AND token = 'WecH+zS6DusN+aVQyvFywyQaTAI3Ah8K9TP7WKSq8sU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}