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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '064c0edea6ee62a21354c2903a301f958e024155b3b1cb49c1e5140c9f485414' 
  AND token = 'OnAraaAHCd0Z4tR+g73T/8GzV7lzSssK0hx9Rw6OJzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}