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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c50d5ba42879ba5a3485e2b3299cc19f0420e97b8b73decfd0236d8f756a6da' 
  AND token = 'ZFuE7KqAOMrr7PPQ3onysxFh97enOi/HdKPJ1vIbIM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}