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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d76166f573a527ac34a262041168f5530fcc60f5a473d1845d3786963185a38' 
  AND token = 'x3Ci6GZLDtR4LDzY4/8mAORiIBNjZRbFiO/L5ITRBhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}