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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b75ce2d8c3c6553c20005664e73ea673608af0ed49fbdf3609ba53dffe763b6' 
  AND token = 'cthm0YKea25hXKHBLFpknWQoyiX/eMyJkZQiPKiv3aw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}