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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9297b4e8c7de33aaf44ab2beb4b007c6bfd3ee4089d02edde4f334025e7dc6df' 
  AND token = 'z+0C3+yRX3hXsq7vvktxyILyZOl4Kq1eaeJEPNJBB2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}