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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddf747d0d0737c8391b0d69b58c0b6e4ad9d76b509a744a235bb59d5e7c5d985' 
  AND token = 'g/o9/mZHypi/6y9PdPRhxC6WAYzrzhIA8aVF0gLTw5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}