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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a75d115592a26df7376b7ad2b1c21c58995286aecd9f946a6d2ce8e247085ac3' 
  AND token = 'aRWL8u6aBUMEoUHB+f0Z3fxdcD50MFE1iJMdJsipwwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}