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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72ff20e4db573e67755f2ac438185e754f9f4d87952a6d27e70bc38be0b797dd' 
  AND token = '3Us/2qeSXZzMpvQ1ILdqwwY8ie+U4FW15ukPTMK8XPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}