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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6381a663b233baef021fcf6726c0f4b23f57e643c6404a78454182f319c51142' 
  AND token = 'BNoi/N6iywNX30r4SNcbGCATJHRIaD/+5HY8Ngfehl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}