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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0641246c3db65071bd6f37304c12c3684dd4b2eeeae802a5e793b6c04072a5b2' 
  AND token = 'JoISATjMpXVyvzLsP9Jo1g46GWztzb/piYbkDpetOfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}