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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81693b2e13929c55f0c0521b76ab32ec7883dfa84f7d937ac5060bf110d0fbb0' 
  AND token = 'mDg4z2tIac0GRgK7lRzcNWDi2ZH6j74zS4zYaAQ/yqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}