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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef4dc3615da961883f521955c991cb4b6f5c82941ca2dcc2bbfc5b1be438f6e6' 
  AND token = 'vjvvMiPAumW98cVHKbzHim2iN1IWp7ygyMDOB8RDE/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}