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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d6430ec39f64eea7bdb8b14d95d0d843ece5da1b9c7bd756f88d3df560f43ff' 
  AND token = 'zIhtdtFCil+d2h55m5ZWIIagC4eqwCbqpj4Z7oYQz48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}