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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce45d1cbc02eab829ae1461a8c12533a16ce3d8ba5be03f5a51bb857d770ec2c' 
  AND token = 'zEF3XglkTyNm3i8vWjRm1cP2V7/dt+gdE08+GIvgvbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}