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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3354a27bf8fc994e230a4788a023a83b4f1f024ad3e046125c21c91b53ce1783' 
  AND token = 'ffKlCnTno5oQnCe+mC8ch/MaEk25+Ml3Ffi265HZAEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}