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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6385a0c2e36b89848e6cb6c131e966ed4c7c4e489535b3f0750499fd1f5560ef' 
  AND token = 's23kfWwj3MdbD/4A6alilbns041WbSmM+qJg46JdGxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}