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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '493fb5b9a05fd0ebb9ec489650b97edffb3d1f5706133d216e13e6dc3f9358bd' 
  AND token = 'c0xLdCuJDCyO/yXzqdzVBVXDoA5Um4ftUR/o1Z+0GZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}