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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66783bf444b700e87dd1d1ca2bdc8e51857656bdff41bbcef92662147a17f7c2' 
  AND token = 'o1B8jROQwpkXK1vOj+e9nO73Xq5Z6p1CgnzdANLd2TA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}