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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25352e0438290e64e171d07dc937798e231cbad49a5c05c2abd2ed59d0283c12' 
  AND token = '+mnraGD5iTTqTXr9jn9OSpIHyPn2EmjGpFjlZRnPG0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}