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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '384f9f6b21cd8532cbcbff57e6a53b02faddf4c485bfa4985562ab468f0509c9' 
  AND token = 'cQjoDdHoxWMmAQB+Roc0gsrlMZ6Oc89Sho+PGSzK5uU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}