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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '499e8b5feff5bb51a9eb3e6484cf28e8f13cb33f3366adea1e76a67521c4d687' 
  AND token = 'MeM9581FKcnljKn+STn0jOU9j4yOltOHnthkKA9JuYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}