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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24482f1fc023c63be7f28d441a360c1b0f1403d62ae2ba1cf63bd28e2fd9dce8' 
  AND token = 'eIqNcygqCb+TSWcO4ltCv7urGyP2LOvcFfMnRfsnzS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}