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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7379523eb80995f23e00d27b1243cdac13ea057705d996a9633e0fce81cde84a' 
  AND token = 'C5QMT1x+ISzZZJMpj3F9gO88Swm5EcJuoyHpDnvkGGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}