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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '93e69e9855da8e6c465414fdb06c47ec8603e20342c160e4afb62e16a1f2f622' 
  AND token = 'GhZHSdVO946dAZ/x+gMYx8VjBA+DDX2aD4kgE83buFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}