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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6252d5d81b8610fdb01f7cca56d45bba0add9f06c9ef3bdcfee96d1df55065bf' 
  AND token = 'xBlJzARX64rVqY371bxhXKjFruXrmXwXcR6yt4s0mXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}