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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf4d32588d2f18dc75a619c711697bf7426203d13806ec2e4340a5c5e17c372b' 
  AND token = 'Wyn00xTq/hPuamumfaVLHrUZCEVVB2DTM5m7HQjoM48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}