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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3f917f0f6c5dcd038b6e148db3e1f7c7d03554503078ab469f236396539e167' 
  AND token = 'yx+IV1rrXMgd1LpEGg86hU/nnyyH4V8fTkIUw3lv2SQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}