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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce53820f4cc126fdd128dca809ae53c819df3339b04871dc025df84f55f3f8d9' 
  AND token = '3AEkOFMsCLFHUAoCFo64ByDI4mmx7mdN2RGpDWgJ0pQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}