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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f6ad558903e27a38a9f72baa4e7baec198d18fec27752371e01cac9b71c19c1' 
  AND token = 'M+HQh39j55QQoU6XztfmNERJaZfwfSbbb4RSSaAGSRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}