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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e779cd917f8bbf5f9df332b10047d9cdac3a978fef354dda155108b5a7e2ca80' 
  AND token = 'olVkBoTiv8+Y8SKdqD/Dc/+G4DiKNlBY0tt0PiwdZgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}