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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2b7ee36a43732a1d00817f6e9b8479828ad48c44e4aa616d72dd577ab493270' 
  AND token = 'qx8XIY/DAujEg8eM/JKccY7tfJj5ZDkjnO9AcBeCHDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}