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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8c6dd56a8c909d119683481e74891979f4c12438b79bc4ec860e15fcfdcbce6' 
  AND token = 'TILTPmhd7xVKVEFUB3D4nPv+BLEx8USELRAhBGuxPh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}