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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4077ba78be7a9eb840fb8aec18e000c5f2d41bea19ec71ba213bdfeb887b9ba7' 
  AND token = '7BZ/MUEGs+/QyG7E/ReT+kdV1fU9s5qiEa1uTcpBsyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}