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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39100afc3d8c6765cfa0a853effd951213a84da22c983a52849d6a5aaf13bd26' 
  AND token = 'VgHOF4WmNXqAAnOV9IOiwPIlpUyEy1qujQg6VhiTp/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}